How much is a bus or train ticket from Boston, MA to San Diego, CA?

All-in bus and train tickets from Boston, MA to San Diego, CA start at $269 one-way on carriers including FlixBus, Amtrak, Greyhound.

How long does the trip from Boston, MA to San Diego, CA take?

The fastest bus or train route from Boston, MA to San Diego, CA takes 56h 55m (07:00 to 15:55).

Where do buses and trains depart in Boston and arrive in San Diego?

Departures in Boston primarily board at Boston South Station (BOS) and arrive in San Diego at San Diego Santa Fe Depot (SAN).

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Boston, MA

All

Bus

Train

Boston, MA → San Diego, CA

Routes from Boston

San Diego to Boston

Terms & Affiliate Disclosure

Privacy

Sun, Nov 15 → Wed, Nov 18

Duration: 76h 5m

•

3 transfers

Brookline

FlixBus #N2605

$34

Book Leg

20:40

Philadelphia Bus Station

03:00

Free Wi-Fi

Outlets

Restroom

Backup 5G eSIM (Saily)

Next day: Mon, Nov 16

Transfer time: 0h 45m

Station info

Philadelphia Bus Station

Greyhound #US0421

$107

Book Leg

03:45

St Louis Bus Station

22:50

Free Wi-Fi

Outlets

Restroom

Backup 5G eSIM (Saily)

Transfer time: 2h 30m

Station info

Next day: Tue, Nov 17

St Louis Bus Station

Greyhound #US1210

$216

Book Leg

01:20

Los Angeles Union Station

15:50

Free Wi-Fi

Outlets

Restroom

Backup 5G eSIM (Saily)

Next day: Wed, Nov 18

Transfer time: 2h 40m

Station info

Los Angeles Union Station

FlixBus #2017

$17

Book Leg

18:30

La Jolla - UC San Diego

21:45

Free Wi-Fi

Outlets

Restroom

$374

Full Route Total • 4 legs

Book Full Route

Book the entire route in one search or book each carrier leg directly:

Full Route Price & Ticket Breakdown

$374 total

1. Boston, MA → Philadelphia, PA

FlixBus Official #N2605 • 20:40–03:00

$34

Book Leg

2. Philadelphia, PA → St Louis, MO

Greyhound Official #US0421 • 03:45–22:50

$107

Book Leg

3. St Louis, MO → Los Angeles, CA

Greyhound Official #US1210 • 01:20–15:50

$216

Book Leg

4. Los Angeles, CA → San Diego, CA

FlixBus Official #2017 • 18:30–21:45

$17

Book Leg