How much is a bus or train ticket from Chicago, IL to Wilmington, NC?

All-in bus and train tickets from Chicago, IL to Wilmington, NC start at $104 one-way on carriers including Amtrak, FlixBus, Greyhound.

How long does the trip from Chicago, IL to Wilmington, NC take?

The fastest bus or train route from Chicago, IL to Wilmington, NC takes 16h 29m (07:30 to 23:59).

Where do buses and trains depart in Chicago and arrive in Wilmington?

Departures in Chicago primarily board at Chicago Transit Station and arrive in Wilmington at Wilmington Transit Station.

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Chicago, IL

All

Bus

Train

Chicago, IL → Wilmington, NC

Routes from Chicago

Wilmington to Chicago

Terms & Affiliate Disclosure

Privacy

Sun, Nov 15 → Mon, Nov 16

Duration: 26h 5m

•

4 transfers

Chicago Bus Station

Greyhound #US0100

$23

Book Leg

14:45

Indianapolis Bus Station

18:50

Free Wi-Fi

Outlets

Restroom

Transfer time: 1h 15m

Station info

Indianapolis Bus Station

Greyhound #US0421

$28

Book Leg

20:05

Columbus Bus Station

23:59

Free Wi-Fi

Outlets

Restroom

Transfer time: 0h 26m

Station info

Next day: Mon, Nov 16

Columbus Bus Station

Greyhound #US0140

$71

Book Leg

00:25

Winston Salem (Trans Center)

10:10

Free Wi-Fi

Outlets

Restroom

Backup 5G eSIM (Saily)

Transfer time: 1h 40m

Station info

Winston Salem (Trans Center)

Greyhound #US0654s

$18

Book Leg

11:50

Raleigh Bus Station

14:20

Free Wi-Fi

Outlets

Restroom

Transfer time: 0h 25m

Station info

Raleigh Bus Station

Greyhound #US0656S

$23

Book Leg

14:45

Wilmington Cape Fear Public Transit

17:50

Free Wi-Fi

Outlets

Restroom

$163

Full Route Total • 5 legs

Book Full Route

Book the entire route in one search or book each carrier leg directly:

Full Route Price & Ticket Breakdown

$163 total

1. Chicago, IL → Indianapolis, IN

Greyhound Official #US0100 • 14:45–18:50

$23

Book Leg

2. Indianapolis, IN → Columbus, OH

Greyhound Official #US0421 • 20:05–23:59

$28

Book Leg

3. Columbus, OH → Winston-Salem, NC

Greyhound Official #US0140 • 00:25–10:10

$71

Book Leg

4. Winston-Salem, NC → Raleigh, NC

Greyhound Official #US0654s • 11:50–14:20

$18

Book Leg

5. Raleigh, NC → Wilmington, NC

Greyhound Official #US0656S • 14:45–17:50

$23

Book Leg