How much is a bus or train ticket from Detroit, MI to San Diego, CA?

All-in bus and train tickets from Detroit, MI to San Diego, CA start at $208 one-way on carriers including Amtrak, Greyhound.

How long does the trip from Detroit, MI to San Diego, CA take?

The fastest bus or train route from Detroit, MI to San Diego, CA takes 43h 8m (07:30 to 02:38).

Where do buses and trains depart in Detroit and arrive in San Diego?

Departures in Detroit primarily board at Detroit Transit Station and arrive in San Diego at San Diego Santa Fe Depot (SAN).

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Detroit, MI

All

Bus

Train

Detroit, MI → San Diego, CA

Routes from Detroit

San Diego to Detroit

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Sun, Nov 15 → Tue, Nov 17

Duration: 59h 25m

•

3 transfers

Detroit Bus Station

Greyhound #US0112

$22

Book Leg

13:50

Indianapolis Bus Station

19:25

Free Wi-Fi

Outlets

Restroom

Backup 5G eSIM (Saily)

Transfer time: 0h 30m

Station info

Indianapolis Bus Station

Greyhound #US0421

$15

Book Leg

19:55

St Louis Bus Station

22:50

Free Wi-Fi

Outlets

Restroom

Transfer time: 2h 30m

Station info

Next day: Mon, Nov 16

St Louis Bus Station

Greyhound #US1210

$157

Book Leg

01:20

Los Angeles Union Station

15:50

Free Wi-Fi

Outlets

Restroom

Backup 5G eSIM (Saily)

Next day: Tue, Nov 17

Transfer time: 2h 40m

Station info

Los Angeles Union Station

FlixBus #2017

$14

Book Leg

18:30

Downtown SD (Seaport)

22:15

Free Wi-Fi

Outlets

Restroom

$208

Full Route Total • 4 legs

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Book the entire route in one search or book each carrier leg directly:

Full Route Price & Ticket Breakdown

$208 total

1. Detroit, MI → Indianapolis, IN

Greyhound Official #US0112 • 13:50–19:25

$22

Book Leg

2. Indianapolis, IN → St Louis, MO

Greyhound Official #US0421 • 19:55–22:50

$15

Book Leg

3. St Louis, MO → Los Angeles, CA

Greyhound Official #US1210 • 01:20–15:50

$157

Book Leg

4. Los Angeles, CA → San Diego, CA

FlixBus Official #2017 • 18:30–22:15

$14

Book Leg